Dr. Thomas has received a $2 million dollar grant from the NIH to study acute & chronic viral infections.
The NIH funded project titled "A Multifaceted Approach to Study Tissue and Cell Type Specific Molecular Mechanisms of the Host Response to Acute/ Chronic Viral Infection" is lead by Dr. Thomas and awarded to the University of Miami School of Medicine. The project is intended to elucidate the tissue specific molecular mechanisms that drive disease progression in patients with chronic viral infections, as these patients are susceptible to high morbidity and mortality rates due to progressive organ damage. The project findings would subsequently be used to identify new targets for therapeutic intervention. Very few viruses are able to manifest as chronic infections in humans. The intrinsic innate immune response provides a first line of defense against invading viruses; however, in the case of chronic viral infections, these initial responses that…